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Release the Data! New Chemical Data, Workshops, and Challenges

By Matthew T. Martin Scientist preparing a well-plate for high-throughput screening. Ever open that cabinet under the kitchen sink, grab that bright blue bottle of window cleaner and wonder exactly...

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Taking a Page from Nature’s Playbook: Innovation for Human Health

By Dustin Renwick Protecting human health through chemical safety remains a priority for EPA, but it’s difficult and expensive to test all the 83,000 or so chemicals currently listed or registered for...

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MCnest: Fly Away Home

By Thomas Landreth  While recent winter weather storms may suggest otherwise, we are getting closer to the time that birds in this hemisphere begin their journey northward. Just like in the 1996 movie,...

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Advancing Chemical Testing by the Thousands

Reposted from EPA Connect, the official blog of EPA leadership. By Bob Kavlock Studying thousands of chemicals at a time with the use of high-tech computer screening models and automated, often...

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Ushering In a New Generation of Chemical Screening

By Richard Judson I work with EPA colleagues and other scientists around the world to integrate advances in biology, biotechnology, chemistry, and computer science to evaluate thousands of chemicals....

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PARIS III: EPA’s Solvent Substitution Software Tool

By Paul Harten, Ph.D. EPA’s PARIS III For decades, companies have used chemicals or solvents to improve the performance of their industrial processes.  Unfortunately, many of these solvents are...

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Globally Linking Scientific Knowledge through the Adverse Outcome Pathways Wiki

By Steve Edwards, Ph.D. I am thrilled to announce that on September 25th, we and our partners released the online Adverse Outcome Pathway (AOP) Wiki—an interactive, virtual encyclopedia for the...

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Advancing Species Extrapolation: EPA’s “Sequence Alignment to Predict Across...

By Carlie A. LaLone, Ph.D. I have been working with a team of EPA colleagues to create an on-line tool, Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS), that will help both...

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Exposing the Missing Link: Advancing Exposure Science to Rapidly Evaluate...

By Tina Bahadori, Sc.D.   Acknowledging that exposure is vital to understanding and preventing human and environmental risks, the National Academies of Science in its 2012 report, “Exposure Science in...

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Exciting Times for Toxicology: Creating New Predictive Models

By Dr. James H. Johnson, Jr. Next week, a number of my EPA colleagues will join toxicologists from across the world in San Diego, CA for the Society of Toxicology’s 54th Annual Meeting and “ToxExpo.”...

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EPA Researchers Win Best Toxicological Paper Awards

EPA scientists Yong Ho Kim, Christina Powers, and Russell S. Thomas were recognized by the Society for Toxicology. By Dina Abdulhadi EPA researchers will be honored March 22, 2015 at the Society of...

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Organs-on-a-Chip: The Future of Chemical Toxicity Testing

By Tom Knudsen, Ph.D. Last week, my colleague Jim Johnson shared a blog post (Exciting Times for Toxicology: Creating New Predictive Models) about EPA’s leadership role to advance chemical toxicity...

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Which Ounces of Prevention? Predictive Toxicology Using Organotypic Models

By Shane Hutson VPROMPT team members (left-to-right) Shane Hutson, Dmitry Markov, John Wikswo and Lisa McCawley. Photo courtesy of Vanessa Allwardt. Everyone knows that “an ounce of prevention is worth...

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